Thermo Fisher Scientific ING1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing ING1 protein. Validated for WB, ICC/IF, and ELISA. Supplied as liquid at 0.25 mg/mL concentration. Suitable for research use in studying tumor suppressor pathways.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| ELISA | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse p33 ING1 N-terminal peptide (KLH conjugate) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735959 |
Product Specific Information
- 0.25 mg/mL was sufficient for detection of PA5-77823 in lysates prepared from human melanoma cell lines by western blot analysis.
- Detects approximately 33 kDa protein.
Target Information
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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