Thermo Fisher Scientific Adiponectin Monoclonal Antibody (OTI1A8), TrueMAB
인체 반응성 Adiponectin 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로 Western Blot에 최적화됨. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 적합. 지방 및 당 대사 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–244 of human ADIPOQ produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates lipid and glucose metabolism. It plays a role in physiological processes such as homeostasis and obesity.
Decreased levels are associated with obesity, insulin resistance, and type 2 diabetes. In mice, adiponectin improves insulin signaling via activation of AMP kinase and PPAR-alpha, enhancing fatty acid transport and oxidation in skeletal muscle, thereby reducing lipid accumulation and improving insulin sensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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