Thermo Fisher Scientific LEF1 Monoclonal Antibody (E.281.8)
LEF1 단백질을 인식하는 Rabbit monoclonal antibody로서 Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC(F), ICC/IF, Flow cytometry 등 다양한 응용에 적합합니다. 고순도 Affinity chromatography로 정제되어 안정적인 결과를 제공합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 | - |
| Flow Cytometry (Flow) | 1:200–1:800 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.281.8 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Pro82 of human LEF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 157 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10987030 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The encoded protein binds to a functionally important site in the T-cell receptor-alpha enhancer, conferring maximal enhancer activity. It is involved in the Wnt signaling pathway and may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors and are linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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