Thermo Fisher Scientific alpha N-Catenin Monoclonal Antibody (T.44.7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:50

View 1 publication 1 publication

Immunoprecipitation (IP)

1:250

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

T.44.7

Immunogen

Synthetic peptide corresponding to the carboxy-terminal sequence of human a-N-Catenin if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha N-Catenin,uniProtId:P26232-1,ncbiNodeId:9606,antigenRange:953,antigenLength:953,antigenImageFileName:MA5-14963_alpha_N-Catenin_P26232-1_Rabbit.svg,antigenImageFileNamePDP:MA5-14963_alpha_N-Catenin_P26232-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10987198

Product Specific Information

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with other -alpha-catenin family members.

Target Information

The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.