Thermo Fisher Scientific alpha N-Catenin Monoclonal Antibody (T.44.7)
Western blot, ICC/IF, IP 등 다양한 응용에 적합한 alpha N-Catenin 단일클론 항체. 인간, 마우스, 랫트 반응성. Rabbit IgG 기반, 비결합형 액상 포맷. 교차반응 없음, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50 | 1 publication |
| Immunoprecipitation (IP) | 1:250 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T.44.7 |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminal sequence of human α-N-Catenin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10987198 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other α-catenin family members.
Target Information
Catenins (α, β, and γ) are cytoplasmic proteins found in various developing and adult tissues. They bind directly or indirectly to the cytoplasmic tail domain of cell adhesion cadherins. The association of catenins with cadherins forms a complex linked to the actin filament network. These complexes are essential for mediating cell adhesion, transducing cell-cell contact signals, and may play a role in cell differentiation.
Alpha-Catenin (CAP102, 102 kDa), initially identified as an E-cadherin-associated protein, also interacts with N-cadherin and P-cadherin family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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