Thermo Fisher Scientific SMC1A Monoclonal Antibody (OTI2D12), TrueMAB
SMC1A 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P)에서 1:500 희석으로 사용 가능. Human, Mouse, Rat에 반응하며, Lyophilized 형태로 제공. 염색체 구조 유지 관련 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 889–1016 of human SMC1A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events requiring chromosomal structural changes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex essential for metaphase progression and sister chromatid cohesion.
Mutations in the SMC1A gene are associated with Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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