Thermo Fisher Scientific GPNMB Monoclonal Antibody (OTI8A10), TrueMAB
인간 GPNMB 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot 및 IHC(P) 적용 가능. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A10 |
| Immunogen | Full length human recombinant protein of human GPNMB produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The GPNMB protein is a type I transmembrane glycoprotein homologous to the pMEL17 precursor, a melanocyte-specific protein.
It is expressed in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic cell lines.
GPNMB may play a role in growth delay and reduction of metastatic potential.
Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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