Thermo Fisher Scientific H3K27ac Monoclonal Antibody (6E7A9)
H3K27ac 단백질을 인식하는 mouse monoclonal antibody로 Western blot, IHC, Flow cytometry, ELISA에 적합. 고순도 Protein G 정제, 1 mg/mL 농도, PBS buffer에 sodium azide 포함. 연구용으로만 사용 가능.
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- MA531761
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- pk
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Thermo Fisher Scientific H3K27ac Monoclonal Antibody (6E7A9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6E7A9 |
| Immunogen | Synthesized peptide of human HIST2H3C (AA: ATKAARK(Ac)SAPATGGV) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787384 |
Product Specific Information
MA5-31761 has been tested in indirect ELISA.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can directly alter chromatin structure or enable binding of specific transcription factors. The N-terminal tail of histone H3 can undergo methylation, acetylation, or phosphorylation, influencing various cellular processes.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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