Thermo Fisher Scientific Bcl-X Polyclonal Antibody
Bcl-X 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 고순도(>95%) 항체로 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human Bcl-X |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803060 |
Product Specific Information
- Purity > 95% by SDS-PAGE.
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. These proteins form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities.
They are located at the outer mitochondrial membrane and regulate the opening of the mitochondrial membrane channel (VDAC), which controls membrane potential, reactive oxygen species production, and cytochrome C release—key factors in apoptosis.
Alternative splicing results in multiple transcript variants encoding two isoforms: the longer isoform acts as an apoptotic inhibitor, while the shorter isoform acts as an apoptotic activator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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