Thermo Fisher Scientific GP130 Polyclonal Antibody
Human 및 Mouse 반응성을 가진 Rabbit Polyclonal GP130 항체로 Western blot, IHC, ICC/IF에 적합. 합성 펩타이드(aa 750-800)를 면역원으로 사용하며, SDS-PAGE 기준 95% 이상 순도. 액상 형태로 제공되며, 항원 친화 크로마토그래피로 정제됨.
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- PA586277
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 750–800 of Human gp130 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2803064 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). It functions as part of the cytokine receptor complex, and activation depends on cytokine binding to their receptors. vIL6, encoded by Kaposi sarcoma-associated herpesvirus, can directly activate this protein bypassing IL6R. Knockout studies in mice indicate a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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