Thermo Fisher Scientific PSMD2 Monoclonal Antibody (OTI1G8), TrueMAB
인간 PSMD2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, ELISA 및 Luminex 분석에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 PBS/BSA/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 1:100–1:1,000 |
| Luminex (LUM) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G8 |
| Immunogen | Full length human recombinant protein of human PSMD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core is composed of four rings of 28 non-identical subunits; two rings consist of seven alpha subunits and two rings consist of seven beta subunits.
The 19S regulator includes a base (with six ATPase and two non-ATPase subunits) and a lid (with up to ten non-ATPase subunits).
Proteasomes are distributed throughout eukaryotic cells at high concentration and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome variant is essential for processing class I MHC peptides.
This gene encodes one of the non-ATPase subunits of the 19S regulator lid. It may also participate in the TNF signaling pathway via interaction with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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