Thermo Fisher Scientific Human NLRP6 Synthetic Peptide
Human NLRP6 단백질의 아미노 말단 16개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 차단용 블로킹 펩타이드로 사용 가능. 인간 시료 반응성, 액상 형태, PBS/BSA 저장. 연구용으로 염증 및 신호전달 연구에 적합.
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Thermo Fisher Scientific Human NLRP6 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human NALP6.
PEP-1136 can be used as a blocking peptide with polyclonal antibody PA5-21022.
Target Information
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins, and are thought to be involved in inflammation and reproduction.
NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC.
Co-expression of NALP6 with ASC results in a synergistic activation of NF-kappa-B and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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