Thermo Fisher Scientific Human NALP7 Synthetic Peptide
인간 NALP7 단백질의 아미노 말단 18개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-21023의 블로킹 펩타이드로 사용 가능. 세포 증식 및 염증 반응 연구에 활용. 정제된 액상 형태로 제공되며 PBS 완충액에 보관.
- 카탈로그번호
- PEP1137
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human NALP7.
PEP-1137 can be used as a blocking peptide with polyclonal antibody PA5-21023.
Target Information
NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, is a member of the PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) and plays a crucial role in cell proliferation.
NALP7 contains a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD), a NACHT domain, and a NACHT-associated domain.
It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain.
NALP7 inhibits caspase-1-dependent interleukin-1β secretion and acts as a feedback regulator of interleukin-1β secretion.
Defects in the NALP7 gene are known to cause hydatidiform mole (HYDM) formation and reduce carcinoma cell line growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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