Thermo Fisher Scientific Human NALP5 Synthetic Peptide
인간 NALP5 단백질의 카르복시 말단 14개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-21021의 블로킹 펩타이드로 사용 가능하며, 염증 및 신경세포 사멸 연구에 활용됩니다. 순도 높은 액상 형태로 제공되며 -20°C에서 보관합니다.
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Thermo Fisher Scientific Human NALP5 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human NALP5.
PEP-1135 can be used as a blocking peptide with polyclonal antibody PA5-21021.
Target Information
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction.
NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice.
Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis.
This suggests that NALP5 may play a role in caspase activation and apoptosis in injured neurons, and could represent a novel target for therapeutic treatment in neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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