Thermo Fisher Scientific MZB1 Polyclonal Antibody
Human MZB1 단백질을 인식하는 Rabbit Polyclonal Antibody. Western Blot 및 IHC(Paraffin)에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 장기보관 시 -20°C 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MZB1. Recombinant protein control fragment (Product #RP-104951) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791274 |
Product Specific Information
Immunogen sequence:
TATAPQLDDE EMYSAHMPAH LRCDACRAVA YQMWQNLAKA ETKLHTSNSG GRRELSELVY TDVLDRS
Target Information
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. It may act as a molecular chaperone or oxidoreductase, displaying low oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. MZB1 helps diversify peripheral B-cell functions by regulating Ca²⁺ stores, antibody secretion, and integrin activation.
Additionally, it acts as a hormone-regulated adipokine/proinflammatory cytokine implicated in chronic inflammation, cellular expansion, and insulin resistance in adipocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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