Thermo Fisher Scientific DMRT1 Monoclonal Antibody (OTI4E12), TrueMAB
DMRT1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 시료 반응성이 있으며, carrier-free 형태로 제공되어 결합 실험에 활용 가능합니다. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–210 of human DMRT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
DMRT1 gene is part of a cluster with two other family members sharing a zinc finger-like DNA-binding motif (DM domain).
The DM domain is a conserved component of the vertebrate sex-determining pathway and regulates male development in flies and nematodes.
This gene shows gonad-specific, sexually dimorphic expression. Mutations can lead to defective testicular development and XY feminization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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