Thermo Fisher Scientific HIV1 gp120 Polyclonal Antibody
HIV-1 gp120 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 액상 형태이며 PBS 및 sodium azide 함유. 연구용으로만 사용 가능.
- 카탈로그번호
- PA520488
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific HIV1 gp120 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 16 amino acid peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155967 |
Product Specific Information
PA5-20488 can be used with blocking peptide PEP-0608.
Target Information
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes.
The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes.
Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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