Thermo Fisher Scientific NR5A1 Monoclonal Antibody (OTI1H2), TrueMAB
Human NR5A1 단백질(아미노산 1-262)에 특이적인 Mouse IgG2a 단클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로만 사용되며 내분비계 발달 관련 SF-1 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–262 of human NR5A1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system.
It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland, and promotes transcriptional activity of steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2) that interact with nuclear receptors, coactivators, and corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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