Thermo Fisher Scientific Phospho-Lyn (Tyr508) Polyclonal Antibody
Lyn 단백질의 Tyr508 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 액상 형태로 연구용에 적합.
- 판매단위
- pk
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Applications 및 Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LYN (Accession P07948), corresponding to amino acid residues around phosphorylated Tyr508 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818288 |
Product Specific Information
Antibody detects endogenous levels of Lyn only when phosphorylated at Tyrosine 507.
Target Information
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well-studied expression of Lyn is in hematopoietic cell types, including lymphoid and myeloid cells, but excluded in T lymphocytes. Lyn plays diverse roles such as regulation of B cell receptor signaling, mast cell signaling, and Epithelial-Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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