
Thermo Fisher Scientific MDC1 Monoclonal Antibody (P2B11), PerCP
MDC1 단백질을 인식하는 PerCP 결합 단클론 항체로, Western blot 및 면역세포염색에 적합합니다. 인간, 생쥐 등 다양한 종에 반응하며, Protein G로 정제된 고순도 항체입니다. DNA 손상 반응 연구용으로 최적화된 제품입니다.
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Thermo Fisher Scientific MDC1 Monoclonal Antibody (P2B11), PerCP
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Chimpanzee, Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | P2B11 |
| Immunogen | GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931740 |
Additional Formats
Product Specific Information
- 0.5 µg/mL of MA5-45286 was sufficient for detection of MDC1 in 10 µg of HeLa cell lysate by ECL immunoblot analysis.
- Detects approximately 184 kDa.
- This antibody recognizes MDC1 at and around the N-terminus.
Target Information
MDC1 participates in the early response to DNA damage. It is a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs, and 13 internal repetitions of a 41 amino acid sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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