Thermo Fisher Scientific TLE1 Monoclonal Antibody (381CT18.5.1)
Human TLE1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot에서 1:100~1:250 희석 비율로 사용 가능. Protein G로 정제된 액상 형태이며, PBS buffer에 sodium azide 포함. 연구용으로 NF-kappa-B 및 Wnt 신호 조절 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:100–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 381CT18.5.1 |
| Immunogen | KLH conjugated synthetic peptide between 199–228 amino acids from the central region of human TLE1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897472 |
Target Information
Transcriptional corepressor that binds to various transcription factors.
Inhibits NF-kappa-B-regulated gene expression and transcriptional activation mediated by FOXA2, CTNNB1, and TCF family members in Wnt signaling.
The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Shows unusual function as a coactivator for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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