Thermo Fisher Scientific CD14 Monoclonal Antibody (B365.1 (B-A8))
인간 CD14 단백질을 인식하는 Mouse IgG1 단클론 항체로, ICC/IF 및 Flow Cytometry에 사용 가능. 비결합형 액상 형태로 제공되며 Protein A로 정제됨. PBS 기반 버퍼에 0.2% BSA와 0.09% sodium azide 포함, 4°C 보관.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:100
- View 2 publications
Flow Cytometry (Flow)
- Tested Dilution: —
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B365.1 (B-A8) |
| Immunogen | Human Monocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_558063 |
Product Specific Information
MA1-23611 detects CD14 Monocyte in Human samples.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils. It functions as a multifunctional lipopolysaccharide receptor and is found both in membrane-bound and soluble forms. CD14 interacts with lipopolysaccharide-binding protein (LBP) to bind LPS molecules and plays a role in immune response regulation, apoptosis recognition, and inflammatory processes. Alternative splicing produces multiple transcript variants encoding the same isoform. CD14 dysfunction is associated with conditions such as Mycobacterium chelonae infection and croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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