Thermo Fisher Scientific RAD51 Monoclonal Antibody (HIS52 (87.6E4))
RAD51 단백질을 인식하는 마우스 단클론 항체로, DNA 복구 연구용에 적합합니다. Rat 시료에서 반응하며, IHC(F) 및 ICC/IF에 사용 가능합니다. 비결합형 액상 형태로 제공되며, Protein G로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Assay-dependent
Immunocytochemistry (ICC/IF)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HIS52 (87.6E4) |
| Immunogen | Stromal cells from rat lymph node |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560929 |
Product Specific Information
This antibody does not react with mouse, guinea pig, rabbit, porcine, goat, ovine, or chicken protein.
Target Information
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recombination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments essential for the homology search and strand exchange. Mutations in the gene can result in breast cancer, mirror movements 2, and Fanconi anemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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