Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI3A4)
Human PDE2A 단백질을 인식하는 Mouse 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 고순도 Affinity Chromatography로 정제된 액상 형태이며, 안정적인 PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A4 |
| Immunogen | Full length human recombinant protein of PDE2A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724967 |
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) with three isoforms (PDE2A1, PDE2A2, PDE2A3) produced by alternative splicing. It degrades both cAMP and cGMP, with higher efficacy for cGMP. PDE2A is expressed in various tissues, most abundantly in the brain, particularly in the cerebellum and neocortex. It has been implicated in penile erectile dysfunction and regulation of fluid and inflammatory cell transport across the endothelial barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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