Thermo Fisher Scientific PYK2 Polyclonal Antibody
Rabbit polyclonal antibody against PYK2 for WB and IP applications. Targets human PTK2B (FAK2) region 275–325. Unconjugated, liquid form, 1 mg/mL concentration. Stored at 4°C and shipped on wet ice for research use only.
- 카탈로그번호
- A304226Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PYK2 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 to 325 of Human Protein Tyrosine Kinase 2 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
PTK2B (FAK2) is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway.
It regulates reorganization of the actin cytoskeleton, cell polarization, migration, adhesion, spreading, and bone remodeling.
FAK2 plays a role in the humoral immune response, maintaining normal levels of marginal B-cells in the spleen and supporting splenic B-cell migration.
Functions downstream of integrin, collagen, immune, G-protein coupled, cytokine, chemokine, and growth factor receptors, mediating responses to cellular stress.
Aberrant FAK2 expression may contribute to cancer cell proliferation, migration, and invasion, with elevated expression observed in gliomas, hepatocellular carcinoma, lung cancer, and breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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