Thermo Fisher Scientific Cyclophilin B Polyclonal Antibody
Human Cyclophilin B에 특이적인 Rabbit Polyclonal Antibody로 Western Blot 및 Immunoprecipitation에 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA580921
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 0.5–2 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of Human Cyclophilin B/PPIB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788185 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human Cyclophilin B/PPIB.
Target Information
Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents—cyclosporin A (CsA) or FK506.
Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP), and those which bind cyclosporin A are called cyclophilins (CyP).
Both CyP:CsA and FKBP:FK506 complexes inhibit calcineurin, a calcium- and calmodulin-dependent protein phosphatase involved in T-cell activation, providing a possible mechanism of immunosuppression by CsA and FK506.
Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase), accelerating protein folding by catalyzing slow steps in proline-containing proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-80921_Cyclophilin_B_P23284-1_Rabbit.svg, PA5-80921_Cyclophilin_B_P23284-1_Rabbit_PDP.jpeg)
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