Thermo Fisher Scientific LOXL2 Polyclonal Antibody
Thermo Fisher Scientific LOXL2 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 다클론 항체입니다. Western blot, IHC, ICC/IF 등에 사용 가능하며 높은 특이성과 재현성을 제공합니다. 항원 친화 크로마토그래피로 정제되어 안정적인 액상 형태로 제공됩니다.
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Thermo Fisher Scientific LOXL2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human LOXL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2792354 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (91%), Rat (91%), Xenopus laevis (83%), Chicken (87%), Bovine (96%).
- Positive Control: HeLa, MDA-MB-231, U87-MG, SK-N-SH, SK-N-AS, 293T transfected with LOXL2, mouse lung.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin.
A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.
The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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