Thermo Fisher Scientific CRYM Monoclonal Antibody (OTI1B5), TrueMAB
CRYM 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, IHC, ICC에 사용 가능. 인간 시료 반응성. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 적합. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Full length human recombinant protein of human CRYM produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Crystallins are divided into two groups: taxon-specific and ubiquitous.
Taxon-specific crystallins are phylogenetically restricted, while ubiquitous crystallins are major structural proteins in vertebrate eye lenses, maintaining transparency and refractive index.
The CRYM gene encodes a taxon-specific crystallin that binds NADPH and shares similarity with bacterial ornithine cyclodeaminases.
Unlike structural crystallins, CRYM binds thyroid hormone and may play regulatory or developmental roles.
Multiple alternatively spliced transcript variants exist for this gene.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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