Thermo Fisher Scientific FADD Monoclonal Antibody (OTI1C11), TrueMAB
인간 FADD 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포 분석에 적합. TrueMAB 포맷으로 높은 특이성과 재현성 제공. 동결건조 형태로 보관 용이하며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C11 |
| Immunogen | Full length human recombinant protein of human FADD produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FADD is an adaptor molecule that mediates apoptotic signals via interactions with cell surface receptors such as TNFRSF6/Fas, TNFRSF25, and TNFSF10/TRAIL.
It recruits caspase-8 through its N-terminal effector domain, activating the cysteine protease cascade.
Knockout studies in mice indicate its essential role in early T cell development.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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