Thermo Fisher Scientific EGR2 Monoclonal Antibody (1G5)
EGR2 단백질을 인식하는 Mouse IgG2b 단클론 항체로, 인간 및 랫트 시료에 반응합니다. Western blot과 ELISA에 적합하며, PBS 버퍼에 보존되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G5 |
| Immunogen | EGR2 (NP_000390.2, 217–293 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
PGLFPMIPDY PGFFPSQCQR DLHGTAGPDR KPFPCPLDTL RVPPPLTPLS TIRNFTLGGP SAGVTGPGAS GGSEGPR
Target Information
The EGR2 gene encodes the early growth response 2 protein, a transcription factor that binds specific DNA regions to regulate gene expression.
EGR2 activates genes involved in the formation and maintenance of myelin, which insulates and protects nerve cells for efficient impulse transmission.
Mutations in the EGR2 gene are associated with Charcot-Marie-Tooth disease types 1D and 4E, and severe congenital hypomyelinating neuropathy (Dejerine-Sottas syndrome).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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