Thermo Fisher Scientific EPHA2 Monoclonal Antibody (1E3)
EPHA2 단백질을 인식하는 Mouse IgG3 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 시료 반응성이 있으며, PBS 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E3 |
| Immunogen | EPHA2 (AAH37166, 204 a.a. ~ 326 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LLQGLAHFPETIAGSDAPS LATVAGTCVDHAVVPPGGEE PRMHCAVDGEW LVPIGQCLCQAGYEKVEDAC QACSPGFFKFEASESPCLEC PEHTLPSPEGATSCECEEGFF RAPQDPASMPCT
Target Information
EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors are implicated in developmental events, particularly in the nervous system. EPHA2 is overexpressed in many human cancers. Tyrosine kinase (TK) proteins regulate cell-cell interactions such as differentiation, adhesion, motility, and apoptosis. Approximately 90 TK genes have been sequenced, including 58 receptor TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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