Thermo Fisher Scientific NFYB Monoclonal Antibody (2H2)
NFYB 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, Western blot 및 ELISA에 적합합니다. Human 시료 반응성이 있으며, Mouse IgG2a 형식의 비결합 항체입니다. 연구용으로 NF-Y 복합체 연구 및 전사 조절 분석에 활용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H2 |
| Immunogen | NFYB (AAH05317, 1–207 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE SFREQDIYLP IANVARIMKN AIPQTGKIAK DAKECVQECV SEFISFITSE ASERCHQEKR KTINGEDILF AMSTLGFDSY VEPLKLYLQK FREAMKGEKG IGGAVTATDG LSEELTEEAF TNQLPAGLIT TDGQQQNVMV YTTSYQQISG VQQIQFS
Target Information
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y consists of three subunits: NF-YA, NF-YB, and NF-YC, all required for DNA binding. The conserved segments in each subunit are homologous to the histone-fold motifs of eukaryotic histones. The DNA-binding domains of NF-YB and NF-YC interact through a histone-fold “handshake” motif, similar to histone H2B and H2A interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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