Thermo Fisher Scientific PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (PMEPA1, 2698)
PMEPA1/TMEPAI 단백질을 인식하는 Mouse monoclonal antibody로, 인간 시료에 반응합니다. IHC 및 Peptide Array에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 암 관련 연구 및 신호전달 경로 분석에 적합합니다.
- 카탈로그번호
- 56937-MSM8-P1ABX
- 판매단위
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Thermo Fisher Scientific PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody (PMEPA1, 2698)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PMEPA1, 2698 |
| Immunogen | Recombinant full-length human PMEPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
PMEPA1 encodes a transmembrane protein containing a Smad interacting motif (SIM).
Expression is induced by androgens and transforming growth factor beta (TGF-β).
The protein suppresses androgen receptor and TGF-β signaling pathways through interactions with Smad proteins.
Overexpression may be involved in various cancers.
Alternatively spliced transcript variants encoding multiple isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: 56937-MSM8-P1ABX_PMEPA1_Q969W9-1_House_mouse.svg)
(이미지: 56937-MSM8-P1ABX_PMEPA1_Q969W9-1_House_mouse_PDP.jpeg)
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