Thermo Fisher Scientific Human IFN-beta Recombinant Protein, PeproTech

Applications

Western Blot (WB)

• Tested Dilution: -
• Publications: 1

ELISA

• Tested Dilution: -
• Publications: 2

Functional Assay

• Tested Dilution: Assay-dependent
• Publications: 1

Inhibition Assays (IA)

• Tested Dilution: -
• Publications: 1

In vitro Assay (IV)

• Tested Dilution: -
• Publications: 92

Miscellaneous PubMed (Misc)

• Tested Dilution: -
• Publications: 18

Product Specifications

Product Specific Information

• Catalog No. 300-02BC-1MG is supplied as 2 × 500 µg (300-02BC-500UG).
• Recombinant Human IFN-beta is a 20.0 kDa protein containing 166 amino acid residues.
• Due to glycosylation, the approximate MW is 22.3 kDa (based on SDS-PAGE and Mass Spectrometry).
• Catalog Number 300-02BC replaces Human IFN-beta (Catalog Number 300-02B).
• Shipped at ambient temperature. Refer to the lot-specific Certificate of Analysis for storage, handling, and reconstitution details.

Target Information

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit tumor development. IFN-beta binding activates tyrosine kinases Jak1 and Tyk2, leading to phosphorylation of STAT transcription factors and expression of immune response genes. Members of the toll-like receptor (TLR) family also stimulate IFN-beta production. Clinically, IFN-beta is used in treatments for tumors, infections, and multiple sclerosis.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.