Thermo Fisher Scientific Neuroserpin Polyclonal Antibody
Neuroserpin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA에 적합합니다. Mouse와 Rat 시료에 반응하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 181–410 of human SERPINI1 (NP_005016.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806152 |
Product Specific Information
Immunogen sequence:
INAVYFKGNW KSQFRPENTR TFSFTKDDES EVQIPMMYQQ GEFYYGEFSD GSNEAGGIYQ VLEIPYEGDE ISMMLVLSRQ EVPLATLEPL VKAQLVEEWA NSVKKQKVEV YLPRFTVEQE IDLKDVLKAL GITEIFIKDA NLTGLSDNKE IFLSKAIHKS FLEVNEEGSE AAAVSGMIAI SRMAVLYPQV IVDHPFFFLI RNRRTGTILF MGRVMHPETM NTSGHDFEEL
Positive Samples: Mouse brain, Rat brain
Target Information
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain and preferentially inhibits tissue-type plasminogen activator. It plays a role in axonal growth regulation and synaptic plasticity development. Mutations in this gene cause familial encephalopathy with neuroserpin inclusion bodies (FENIB), a dominantly inherited encephalopathy and epilepsy characterized by mutant neuroserpin polymer accumulation. Multiple alternatively spliced variants encoding the same protein have been identified.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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