
Thermo Fisher Scientific SLC22A2 Polyclonal Antibody
SLC22A2 단백질을 인식하는 토끼 폴리클로나 항체로, Western blot에 적합합니다. 사람, 생쥐, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포막 단백질 검출에 유용하며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human SLC22A2 aa 44–150/555 (Extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2913504 |
Product Specific Information
- Positive Control: HepG2 cell lysate, 293T cell lysate, rat brain tissue lysate, mouse kidney tissue lysate, mouse brain tissue lysate
- Subcellular Location: Membrane
Target Information
Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from various tissues, functioning in the elimination of endogenous amines, cationic drugs, and xenobiotics. OCTs have a 12-transmembrane-domain structure and a large extracellular hydrophilic loop.
In humans:
- OCT1 is primarily expressed in the liver.
- OCT2 (SLC22A2) is expressed in the kidney and mediates pH-sensitive tubular uptake of organic compounds.
- OCT3 is expressed in placenta, skeletal muscle, prostate, aorta, and liver.
An additional splice variant exists for OCT2, known as OCT2-A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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