Thermo Fisher Scientific MAGI3 Polyclonal Antibody
MAGI3 단백질을 인식하는 Thermo Fisher Scientific의 sheep 유래 polyclonal antibody입니다. Western blot 등 연구용 분석에 적합하며, PBS 버퍼와 sodium azide를 포함한 액상 형태입니다. PDZ domain 4-5 기반 immunogen으로 제작되어 세포 신호 조절 연구에 활용 가능합니다.
- 카탈로그번호
- PA112323
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific MAGI3 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to PDZ domain 4-5 of MAGI-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2234871 |
Target Information
Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a 130 kDa guanylate kinase belonging to a family of multi-PDZ domain-containing kinases localized at epithelial cell tight junctions.
MAGI3 cooperates with PTEN/MMAC to modulate AKT/PKB kinase activity, positioning PTEN/MMAC phosphatase at subcellular sites involved in cell proliferation and survival regulation.
This protein family typically includes an N-terminal guanylate kinase domain, a WW domain containing two conserved tryptophan residues (first identified in mouse YAP65), followed by five PDZ domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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