Thermo Fisher Scientific MAGI3 Polyclonal Antibody
MAGI3 단백질을 인식하는 sheep polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, PBS 용액에 0.08% sodium azide가 포함된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to the guanylate kinase-WW domain of MAGI-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2250168 |
Product Specific Information
PA1-12324 detects a band at approximately 130 kDa in Western blot applications.
Target Information
Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a 130 kDa guanylate kinase that belongs to a family of multi-PDZ domain-containing guanylate kinases localized to epithelial cell tight junctions.
MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to subcellular locations involved in regulating cell proliferation and survival.
MAGI3 and related proteins contain an N-terminal guanylate kinase domain, a WW domain characterized by two conserved tryptophan residues, and five PDZ domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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