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Thermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)
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Thermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)

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Recombinant mouse monoclonal antibody targeting human CD61 (Integrin beta-3). Validated for IHC(P). Expressed in HEK293 cells, purified via Protein A/G. Supplied as liquid at 200 µg/mL in PBS with BSA and sodium azide. For research use only.

카탈로그번호
3690-MSM4-P1
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 07:09
Thermo Fisher Scientific 3690-MSM4-P1 CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713) pk판매 단위 pk ·
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975,200원VAT 포함 1,072,720원

Thermo Fisher Scientific · Thermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested dilution: 1–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1, kappa
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone rITGB3, 1713
Immunogen Recombinant full-length human CD61 (Integrin beta 3) protein (UniProt ID: P05106-1, 1–788 aa)
Conjugate Unconjugated
Form Liquid
Concentration 200 µg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4, with 0.05% BSA
Contains 0.05% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • For immunohistochemistry on PFA-fixed tissues, incubate antibody for 30 minutes at room temperature.
  • Formalin-fixed tissues require heat-induced antigen retrieval in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

CD61 (GPIIIa, ITGB3) is a glycoprotein expressed on megakaryocytes, platelets, and their precursors. It functions as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin, playing a key role in platelet aggregation and adhesion.

  • Molecular weight: ~105 kDa
  • Forms complexes with CD41 (αIIb integrin) or CD51 (αV integrin)
  • Expressed on platelets, megakaryocytes, endothelial cells, monocytes, and osteoclasts
  • Involved in cell adhesion and signaling
  • Associated disorders: Glanzmann Thrombasthenia, Platelet-type 16 Bleeding Disorder

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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