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Thermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)
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Thermo Fisher Scientific

Thermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)

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Recombinant mouse monoclonal antibody targeting human CD61 (Integrin beta-3). Validated for IHC(P). Expressed in HEK293 cells, purified via Protein A/G. Supplied as liquid at 200 µg/mL in PBS with BSA and sodium azide. For research use only.

브랜드
Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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Thermo Fisher Scientific 3690-MSM4-P1 CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713) pk판매 단위 pk
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975,200원VAT 포함 1,072,720원
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Thermo Fisher Scientific · Thermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested dilution: 1–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1, kappa
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone rITGB3, 1713
Immunogen Recombinant full-length human CD61 (Integrin beta 3) protein (UniProt ID: P05106-1, 1–788 aa)
Conjugate Unconjugated
Form Liquid
Concentration 200 µg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4, with 0.05% BSA
Contains 0.05% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • For immunohistochemistry on PFA-fixed tissues, incubate antibody for 30 minutes at room temperature.
  • Formalin-fixed tissues require heat-induced antigen retrieval in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

CD61 (GPIIIa, ITGB3) is a glycoprotein expressed on megakaryocytes, platelets, and their precursors. It functions as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin, playing a key role in platelet aggregation and adhesion.

  • Molecular weight: ~105 kDa
  • Forms complexes with CD41 (αIIb integrin) or CD51 (αV integrin)
  • Expressed on platelets, megakaryocytes, endothelial cells, monocytes, and osteoclasts
  • Involved in cell adhesion and signaling
  • Associated disorders: Glanzmann Thrombasthenia, Platelet-type 16 Bleeding Disorder

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Thermo Fisher Scientific 상품 둘러보기

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Thermo Fisher ScientificThermo Fisher Scientific CD61/Integrin 3/Platelet Glycoprotein IIIa (Platelet Marker) Monoclonal Antibody (ITGB3/2145)449,700원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific CD61/Integrin 3/Platelet Glycoprotein IIIa (Platelet Marker) Monoclonal Antibody (ITGB3/2145)900,300원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)975,200원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific CD61/Integrin beta-3/Platelet Glycoprotein IIIa Recombinant Mouse Monoclonal Antibody (rITGB3, 1713)522,100원VAT별도

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