Thermo Fisher Scientific CD44 v3-v10 Polyclonal Antibody
CD44 v3-v10 폴리클로날 항체로 인간 CD44 항원을 특이적으로 인식. 파라핀 및 동결 조직 면역조직화학(IHC)에 사용 가능. 고트 IgG 기반 비결합형 액상 항체로 연구용에 적합. 세포 부착, 이동 및 암 전이 관련 연구에 활용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 20 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 50 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human CD44v3-v10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C or -20°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_2550595 |
Product Specific Information
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections.
A suggested positive control for immunohistochemical applications is breast carcinoma and colon adenocarcinoma.
Target Information
CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain, and by some epithelial cells of the intestine and breast.
Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration.
It also participates in lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in some carcinomas, potentially related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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