Thermo Fisher Scientific MAD2L1BP Polyclonal Antibody
Rabbit polyclonal antibody against human MAD2L1BP for WB and ICC/IF applications. Recombinant immunogen-based, antigen affinity purified, unconjugated form. Suitable for research use in cell cycle and spindle checkpoint studies.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MAD2L1BP. Recombinant protein control fragment (Product #RP-104592) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663325 |
Product Specific Information
Immunogen sequence:
PDLEWYEKSEE THASQIELLE TSSTQEPLNA SEAFCPRDCM VPVVFPGPVS QEGCCQFTCE LLKHIMYQRQ QLPLPY
Highest antigen sequence identity to the following orthologs:
- Mouse: 72%
- Rat: 73%
Target Information
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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