Thermo Fisher Scientific WIPI1 Polyclonal Antibody
WIPI1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 적합합니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 자가포식 관련 단백질 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | – |
| Immunohistochemistry (IHC) | 20 µg/mL | – |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid synthetic peptide near the carboxy terminus of human WIPI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551804 |
Product Specific Information
- A suggested positive control is rat colon lysate.
- PA5-34452 can be used with blocking peptide PEP-1494.
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as ATG18 or WIPI49, is involved in autophagy and may regulate protein trafficking in recycling pathways.
It contains three WD repeats forming a seven-bladed propeller structure, facilitating interaction with other proteins.
WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network.
It is ubiquitously expressed, with highest levels in heart, testis, placenta, pancreas, and skeletal muscle.
WIPI1 is upregulated in various tumors, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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