Thermo Fisher Scientific Transthyretin Polyclonal Antibody
인간 Transthyretin(TTR)에 반응하는 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry에 사용 가능. KLH 결합 합성 펩타이드(aa 47–74)로 면역. 고순도(2 mg/mL) 액상 형태, PBS buffer 및 sodium azide 포함. 연구용 한정.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 47–74 amino acids from the central region of human TTR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2212102 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that transports thyroxine and retinol-binding protein. It is primarily produced in the liver and secreted into plasma. TTR constitutes approximately 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the CNS. It is associated with neuritic plaques, neurofibrillary tangles, and microangiopathic lesions in senile cerebral amyloid. Over 40 mutations in the TTR gene are linked to amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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