Thermo Fisher Scientific TPO Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:1,000 dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MRALAVLSVT LVMACTEAFF PFISRGKELL WGKPEESRVS SVLEESKRLV DTAMYATMQR NLKKRGILSA AQLLSFSKLP EPTSGVIARA AEIMETSIQA MKRKVNLKTQ QSQHPTDALS EDLLSIIANM SGCLPYMLPP KCPNTCLANK YRPITGACNN RDHPRWGASN TALARWLPPV YEDGFSQPRG WNPGFLYNGF PLPPVREVTR HVIQVSNEVV TDDDRYSDLL MAWGQYIDHD IAFTPQSTSK AAFGGGADCQ MTCENQNPCF PIQLPEEARP AAGTACLPFY RSSAACGTGD QGALFGNLST ANPRQQMNGL TSFLDASTVY GSSPALERQL RNWTSAEGLL RVHARLRDSG RAYLPFVPPR APAACAPEPG IPGETRGPCF LAGDGRASEV PSLTALHTLW LREHNRLAAA LKALNAHWSA DAVYQEARKV VGALHQIITL RDYIPRILGP EAFQQYVGPY EGYDSTANPT VSNVFSTAAF RFGHATIHPL VRRLDASFQE HPDLPGLWLH QAFFSPWTLL RGGGLDPLIR GLLARPAKLQ VQDQLMNEEL TERLFVLSNS STLDLASINL QRGRDHGLPG YNEWREFCGL PRLETPADLS TAIASRSVAD KILDLYKHPD NIDVWLGGLA ENFLPRARTG PLFACLIGKQ MKALRDGDWF WWENSHVFTD AQRRELEKHS LSRVICDNTG LTRVPMDAFQ VGKFPEDFES CDSITGMNLE AWRETFPQDD KCGFPESVEN GDFVHCEESG RRVLVYSCRH GYELQGREQL TCTQEGWDFQ PPLCKDVNEC ADGAHPPCHA SARCRNTKGG FQCLCADPYE LGDDGRTCVD SGRLPRVTWI SMSLAALLIG GFAGLTSTVI CRWTRTGTKS TLPISETGGG TPELRCGKHQ AVGTSPQRAA AQDSEQESAG MEGRDTHRLP RAL

Target Information

Thyroid Peroxidase (TPO)는 갑상선의 정상 기능에 필수적인 효소로, 티로글로불린 내 티로신 잔기의 요오드화 및 요오드화된 티로신 간의 페녹시 에스터 결합 형성을 촉진하여 갑상선 호르몬(티록신, 트리요오드티로닌) 생성을 담당합니다.
이 유전자의 돌연변이는 선천성 갑상선기능저하증, 선천성 갑상선종, 갑상선 호르몬 유기화 결함 IIA와 같은 질환과 관련이 있습니다.
여러 전사 변이체가 보고되었으나, 일부 변이체의 전체 길이는 아직 명확히 규명되지 않았습니다.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.