Thermo Fisher Scientific CD170 (Siglec F) Recombinant Rabbit Monoclonal Antibody (110), PE

Applications

• Flow Cytometry (Flow): Assay-dependent

Product Specifications

Additional Formats

• Unconjugated
• FITC
• Request custom conjugation

Product Specific Information

This antibody may be stored for up to twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze.
Contains sodium azide, which is toxic to cells; dispose of properly by flushing with large volumes of water.

Target Information

SIGLEC5 (CD170) is a putative adhesion molecule mediating sialic acid-dependent binding to cells. It binds both α2,3-linked and α2,6-linked sialic acids. The recognition site may be masked by cis interactions on the same cell surface.
SIGLEC5 is expressed by monocytic/myeloid lineage cells and is abundant in peripheral blood leukocytes, spleen, and bone marrow, with lower expression in lymph node, lung, appendix, placenta, pancreas, and thymus. It is found in monocytes and neutrophils but absent from leukemic cell lines representing early myelomonocytic differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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