Thermo Fisher Scientific MSI2 Monoclonal Antibody (OTI2F10), TrueMAB
MSI2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC/IF에 사용 가능. Human 시료 반응성. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. 줄기세포 유지 및 뇌 손상 회복 관련 연구에 적합.
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Thermo Fisher Scientific MSI2 Monoclonal Antibody (OTI2F10), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F10 |
| Immunogen | Full length human recombinant protein of human MSI2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid cytoplasmic protein containing two RNA recognition motif (RRM) domains.
It is expressed ubiquitously at low levels and functions as an RNA-binding protein regulating target mRNA expression, contributing to stem cell proliferation and maintenance in the central nervous system.
Msi2 is phosphorylated posttranslationally and upregulated after brain injury, suggesting roles in tissue regeneration.
Chromosomal aberrations involving Msi2 are linked to chronic myeloid leukemia progression.
Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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