Thermo Fisher Scientific NME1 Recombinant Rabbit Monoclonal Antibody (001)
Human NME1/NDKA 단백질에 특이적인 재조합 토끼 단클론 항체로, WB, ICC/IF, ELISA 등 다양한 응용 가능. 높은 특이성 및 일관된 로트 간 재현성 제공. 방부제 무첨가이며 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 001 |
| Immunogen | Recombinant Human NME1/NDKA protein (Ala2–Glu152) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786398 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human NME1/NDKA.
Target Information
NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in this gene have been found in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been identified. Co-transcription of NME1 and NME2 generates naturally occurring transcripts (NME1-NME2), which encode a fusion protein sharing identity with each individual gene product.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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