Thermo Fisher Scientific NF-kappaB1 Polyclonal Antibody
NF-kappaB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합. 세포 성장, 분화, 염증 등 NF-kB 관련 신호전달 연구에 활용. 연구용 한정 제품.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 918 and 968 of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
NF-kB is a nuclear transcription factor activated by various extracellular and intracellular stimuli such as cytokines, UV radiation, stress, injury, and bacterial or viral products. It regulates key cellular events including growth, differentiation, proliferation, apoptosis, and inflammation.
NFKB1 (p50), a 50 kDa functional subunit of NF-kB, belongs to the Rel protein family and is synthesized as a p105 precursor containing an N-terminal RHD region with nuclear localization, DNA-binding, and dimerization domains. NFKB1 (p50) can form homodimers or heterodimers with p65 to constitute the functional NF-kB factor.
NF-kB plays important roles in immune response and has been implicated in diseases such as AIDS, hematogenic cancer metastasis, and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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