Thermo Fisher Scientific NF-kappaB2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt.

Target Information

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB).
The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function.
The encoded protein can act as a transcriptional activator or repressor depending on its dimerization partner.
The full-length p100 protein is co-translationally processed into a p52 active form.
Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may lead to fusion proteins.
A pseudogene for this gene exists on chromosome 18, and alternative splicing produces multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.