Thermo Fisher Scientific PLAGL1 Monoclonal Antibody (1E2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

1E2

Immunogen

PLAGL1 (NP_002647.2, 221 a.a. approximately 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLAGL1,uniProtId:Q9UM63-1,ncbiNodeId:9606,antigenRange:221-320,antigenLength:463,antigenImageFileName:H00005325-M01A_PLAGL1_Q9UM63-1_House_mouse.svg,antigenImageFileNamePDP:H00005325-M01A_PLAGL1_Q9UM63-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: QPMQPLPESL ASLHPSVSPG SPPPPLPNHK YNTTSTSYSP LASLPLKADT KGFCNISLFE DLPLQEPQSP QKLNPGFDLA KGNAGKVNLP KELPADAVNL

Target Information

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5` UTR and encoding two different isoforms, have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.