Thermo Fisher Scientific Perilipin 1 Monoclonal Antibody (GT2781)
Perilipin 1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (GT2781). Western blot, IHC, ICC 등 다양한 응용 가능. Human과 Mouse 반응성, Protein G 정제, PBS/glycerol 용액 형태. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT2781 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Perilipin (proprietary sequence) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 20% glycerol |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735308 |
Product Specific Information
- Positive Control: Mouse adipose
- Predicted Reactivity: Human (100%), Rat (92%), Pig (92%), Sheep (94%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Adipose tissue acts as an energy reserve in animals and is tightly regulated in nondomestic species. Adipose cells produce and secrete numerous physiologically important proteins, including lipoprotein lipase (LPL), leptin, Acrp30, resistin, and perilipin.
Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated and localized exclusively to the surface of lipid droplets. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A, leading to inhibition of hormone-sensitive lipase (HSL), which mediates triacylglycerol hydrolysis—the major stored energy form in the body.
Perilipin expression is limited to adipocytes and steroidogenic cells. Two isoforms, Perilipin A and B, are known and are encoded by a single-copy gene resulting from differential splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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